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Intubation and Rapid Sequence Induction
By Pat Neligan


All tutorials located on this site are the property of Patrick Neligan and are for personal study purposes only. They are not peer reviewed and no responsibility is taken for inaccuracies. These tutorials must not be reproduced without permission or used in any other publication.

Contents

1. Why we intubate patients.

2. Types of endotracheal tubes.

3. Laryngoscopes.

4. The process of intubation.

5. Rapid sequence induction


Why do we intubate patients?

1. Maintenance of a clear airway

Particularly when the patient is on his / her side, face down or head down. Moreover if the patient is edentulous, obese or has a large tongue or beard, it may be difficult to maintain the airway even in the supine position. The laryngeal mask airway has loosened some of these reasons, and is often used now where an endotracheal tube (ett) would have been used in the past.

2. Protection of the trachea and lungs

The ett prevents the aspiration of blood, mucus, gastric acid (which may regurgitate) or vomit. Materials such as these may cause pneumonitis or bronchial obstruction (leading to airway collapse).

3. Tracheobronchial Toilet

The ett facilitates removal of mucus and other undesirable material from the airway.

4. Controlled mechanical ventilation

Traditionally mechanical ventilation has been performed through an ett. The cuff on the ett provides a good seal and guarantees the selected tidal volume. However controlled ventilation can also be given by 1. Laryngeal mask airways, 2. Tracheostomies, 3. Non invasive face masks.

 

 

Endotracheal Tubes

  • There are a number of different types of endotracheal tubes.
  • The commonest type is a plastic curved tube with a cuff which is fixed to the outer surface of the distal end. The cuff is inflated with air to provide a seal between the tube and the inner lining of the trachea. There is a amall indicator balloon which is attached by a small tube to the endotracheal tube. This serves to indicate that the cuff is inflated / deflated
  • On the side of the tube the internal diameter is indicated: eg. 8.0 = 8cm internal diameter. This is the size of the tube. Smaller tubes are associated with increased resistance to gas flow. Larger tubes may damage the trachea. For most women a 7.5mm ETT will suffice, and a size 8.0 –8.5 for most men. The 7.5mm ETT will actually work well for most patients.
  • These tubes are usually cut so that they don’t slip too far down and enter one of the main bronchi, thus ventilating only one lung.
  • For most women the tube is sited at 19 – 20cm at lip level. For most men this is 21 – 23cm.

Other types of ETT.

  • Uncuffed tubes: used in children under the age of 12. This is because the paediatric airway is narrowest in the sub glottic area, and it is essential that the fit is not too tight or else there will be necrosis of the mucosal lining. When intubating a child there must always be an audible leak.
  • Reinforced Tubes

These are used under certain circumstances in theatre where there is concern that the ett withh be daamaged or kinked. The tube contains an internal metal ring that looks like a spring. The problem with these tubes is that they cannot be cut and tend to slide down one bronchus.

  • Double Lumen Tubes

These are used in thoracic anaesthesia in order to preferentially ventilate one lung and allow the other lung to collapse. They are rarely used in ICU, the exception being in lung contusions, where it may be impossible to ventilate the sick lung without damaging the healthy one.

  • Southfacing Tubes

These are used in ENT and dental surgery. They have no role in ICU as suction can only be performed through them with difficulty.

  • Northfacing tubes.

These are used for nasal intubations in faciomaxillary surgery. Again they have no role in ICU. Nasal intubations in ICU are usually performed with standard etts.

Laryngoscopes

  • Laryngoscopes are the instruments used for performing intubations. A laryngoscope consists of a blade, of varying sizes (1 to 4), which includes a fibreoptic light source, and a handle, which contains the power source for the light.
  • For most laryngoscopes the blade is curved. For small babies, on uses a straight blade. This is because the technique for intubating infants is different.

 

The process of intubation

  1. Head positioning: this is the single most important aspect from a nursing point of view. Do not remove the pillow. The correct position for the head is "sniffing the morning air", with the neck slightly flexed and the head extended. One places a pillow under the head and neck but NOT under the shoulders. This allows a straight line of vision from the mouth to the vocal cords."sniffing the morning air" position
  2. The laryngoscope is introduced into the right hand side of the mouth (it is held by the left ahnd). The tongue is swept to the left and the tip of the blade is advanced until a fold of skin / cartilage is visualised at twelve o’ clock. This is the epiglottis, and this sits over the glottis (the opening of the larynx) during swallowing.
    inserting the laryngoscope

  3. The tip of the blade is advanced to the base of the epiglottis, known as the vallecula, and the entire laryngoscope is lifted upwards and outwards. This flips the epiglottis upwards and exposes the glottis below. An opening is seen with two white vocal cords forming a triangle on each side.

  4. normal laryngeal anatomy

  5. The tip of the endotracheal tube is advanced through the vocal cords and once the cuff has passed through, one stops advancing. The tube is secured at this level and the cuff inflated.
  6. There are two types of cuff: high pressure-low volume (which takes 2-3ml of air) and high volume-low pressure (30 – 50ml of air). The principle with both is the same: the cuff is inflated until the leak is abolished; no more, no less. Too high a cuff pressure will necrose the tracheal mucosa (by cutting off it’s circulation) and cause a tracheal stricture.
  7. The tube may be secured in a variety of ways, all that is important is that it is held tightly, and can not slide up and down the trachea.

Rapid Sequence Induction

  • When anaesthetising patients for emergency surgery, anaesthetists use a process called a "rapid sequence induction". The objective is to secure the airway rapidly and prevent soiling of the lungs with gastric contents.
  • We call this "the full stomach". This indicates that for some reason, the stomach is considered full of material; the patient need not have eaten recently.
  • Reasons for having a "full stomach"
  1. Recent meal
  2. Delayed gastric emptying: trauma, acute abdomen, morphine.
  3. Incompetant lower oesophageal sphincter: obesity, hiatus hernia, pregnancy
  • The patient goes asleep with the aid of an intravenous induction agent: thiopentone or propofol. These cause hypnosis and amnesia.
  • To rapidly intubate the larynx, it is important to have a high degree of muscle relaxation very quickly. The drug used for this is suxamethonium. This acts by causing every muscle in the body to contract, and subsequently relax. The result of this is the sudden release of a lot of potassium into the bloodstream. Suxamethonium is contraindicated if there is hyperkalaemia, as it may cause cardiac arrest. Because it causes such widespread muscle contraction (rather like "cramping"), patients usually complain of muscle pains the next day.
  • It is not conventional to premedicate patients undergoing rapid sequence induction or to administer sedatives such as midazolam or fentanyl prior to the administration of anaesthesia. The reason for this is that if you are unable to intubate the patient, then the anaesthetic agents will wear off and the patient will wake up within 5 mins, thus not putting the airway at risk.
  • We avoid manually ventilating patients undergoing rapid sequence induction, as this inflates the stomach and encourages regurgitation.

The procedure of rapid sequence induction:

  1. Preparation:
  2. Drugs: thiopentone, suxamethonium, atropine, ephedrine.

    Endotracheal tubes: a variety of sizes available and cut and checked (to make sure that the cuff is intact -–ie. Not punctures)

    Laryngoscopes – 2 functioning laryngoscopes with a variety of blades.

    Suction – on and under the pillow.

    A Gum elastic bougie – to railroad the ETT is there is difficulty in placing the ett.

    An intravenous cannula, with a free-flowing drip

  3. Monitoring:
  4. Blood pressure, ECG, pulse oximetery, end tidal CO2 (if available).

  5. Assistant:
  6. This person must be familiar with the RSI process and be able to apply cricoid pressure. The cricoid carthilage is the ring felt below the larynx. If this is displaced posteriorly, because it is circular shaped and solid, it compresses and closes the oesophagus (which lies behind it). This prevents passive regurgitation of gastric contents.

  7. Induction:

The patient is preoxygenated for a full three minutes, to wash all of the nitrogen out of the lungs and create a resevoir of O2.

Thiopentone is administered, cricoid pressure is applied, followed by suxamethonium.

applying cricoid pressure

The patient is asleep when the eyelash reflex is lost, and relaxed when fasciculation stops.

The patient is intubated, the cuff inflated and the tube secured. Cricoid pressure is not released until the anaesthetist is happy that the tube is correctly placed. This is established by listening for bilateral breath sounds, observing uniform bilateral chest movement and an etCO2 trace (if available).

 

5. Anaesthesia

When the anaesthetist is happy that the airway is intact, he administers the remainder of the anaesthetic agents - fentanyl, nitrous oxide and the volatile agent which maintains anaesthesia (e.g. isoflurane). A non depolarising neuromuscular blocker may be added now to maintain muscle relaxation for the duration.

6. Emergence

At the completion of surgery, the anaesthetic agent is turned off, 100% oxygen is administered, neuromuscular blockade is reversed and the patient is permitted to emerge from anaesthesia. The risk of aspiration of gastric contents is as high now as at the beginning. The airway is carefully cleaned with suction and the ett remains in situ until the patient is fully awake, lying on their side and is able to remove the tube themselves.


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