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Intubation
and Rapid Sequence Induction
By Pat Neligan
All
tutorials located on this site are the property of Patrick
Neligan and are for personal study purposes only. They are not
peer reviewed and no responsibility is taken for inaccuracies. These
tutorials must not be reproduced without permission or used in any
other publication.
Contents
1. Why we intubate patients.
2. Types of endotracheal tubes.
3. Laryngoscopes.
4. The process of intubation.
5. Rapid sequence induction
Why do we intubate patients?
1. Maintenance of a clear airway
Particularly when the patient is on his / her side, face down or head
down. Moreover if the patient is edentulous, obese or has a large tongue
or beard, it may be difficult to maintain the airway even in the supine
position. The laryngeal mask airway has loosened some of these reasons,
and is often used now where an endotracheal tube (ett) would have been
used in the past.
2. Protection of the trachea and lungs
The ett prevents the aspiration of blood, mucus, gastric acid
(which may regurgitate) or vomit. Materials such as these may cause
pneumonitis or bronchial obstruction (leading to airway collapse).
3. Tracheobronchial Toilet
The ett facilitates removal of mucus and other undesirable material
from the airway.
4. Controlled mechanical ventilation
Traditionally mechanical ventilation has been performed through an
ett. The cuff on the ett provides a good seal and guarantees the
selected tidal volume. However controlled ventilation can also be given
by 1. Laryngeal mask airways, 2. Tracheostomies, 3. Non invasive face
masks.
Endotracheal Tubes
There are a number of different types of endotracheal tubes.
The commonest type is a plastic curved tube with a cuff which is
fixed to the outer surface of the distal end. The cuff is inflated
with air to provide a seal between the tube and the inner lining of
the trachea. There is a amall indicator balloon which is attached by a
small tube to the endotracheal tube. This serves to indicate that the
cuff is inflated / deflated
On the side of the tube the internal diameter is indicated: eg. 8.0
= 8cm internal diameter. This is the size of the tube. Smaller tubes
are associated with increased resistance to gas flow. Larger tubes may
damage the trachea. For most women a 7.5mm ETT will suffice, and a
size 8.0 8.5 for most men. The 7.5mm ETT will actually work well
for most patients.
These tubes are usually cut so that they dont slip too far down
and enter one of the main bronchi, thus ventilating only one lung.
For most women the tube is sited at 19 20cm at lip level. For
most men this is 21 23cm.
Other types of ETT.
- Uncuffed tubes: used in children under the age of 12. This is
because the paediatric airway is narrowest in the sub glottic area,
and it is essential that the fit is not too tight or else there will
be necrosis of the mucosal lining. When intubating a child there must
always be an audible leak.
- Reinforced Tubes
These are used under certain circumstances in theatre where there is
concern that the ett withh be daamaged or kinked. The tube contains an
internal metal ring that looks like a spring. The problem with these
tubes is that they cannot be cut and tend to slide down one bronchus.
These are used in thoracic anaesthesia in order to preferentially
ventilate one lung and allow the other lung to collapse. They are
rarely used in ICU, the exception being in lung contusions, where it
may be impossible to ventilate the sick lung without damaging the
healthy one.
These are used in ENT and dental surgery. They have no role in ICU
as suction can only be performed through them with difficulty.
These are used for nasal intubations in faciomaxillary surgery.
Again they have no role in ICU. Nasal intubations in ICU are usually
performed with standard etts.
Laryngoscopes
Laryngoscopes are the instruments used for performing intubations. A
laryngoscope consists of a blade, of varying sizes (1 to 4), which
includes a fibreoptic light source, and a handle, which contains the
power source for the light.
For most laryngoscopes the blade is curved. For small babies, on
uses a straight blade. This is because the technique for intubating
infants is different.
The process of intubation
Head positioning: this is the single most important aspect from a
nursing point of view. Do not remove the pillow. The correct position
for the head is "sniffing the morning air", with the neck
slightly flexed and the head extended. One places a pillow under the
head and neck but NOT under the shoulders. This allows a straight line
of vision from the mouth to the vocal cords.
The laryngoscope is introduced into the right hand
side of the mouth (it is held by the left ahnd). The tongue is swept
to the left and the tip of the blade is advanced until a fold of skin
/ cartilage is visualised at twelve o clock. This is the
epiglottis, and this sits over the glottis (the opening of the larynx)
during swallowing.

The tip of the blade is advanced to the base of the
epiglottis, known as the vallecula, and the entire laryngoscope is
lifted upwards and outwards. This flips the epiglottis upwards and
exposes the glottis below. An opening is seen with two white vocal
cords forming a triangle on each side.

The tip of the endotracheal tube is advanced through the vocal cords
and once the cuff has passed through, one stops advancing. The tube is
secured at this level and the cuff inflated.
There are two types of cuff: high pressure-low volume (which takes
2-3ml of air) and high volume-low pressure (30 50ml of air). The
principle with both is the same: the cuff is inflated until the leak
is abolished; no more, no less. Too high a cuff pressure will necrose
the tracheal mucosa (by cutting off its circulation) and cause a
tracheal stricture.
The tube may be secured in a variety of ways, all that is important
is that it is held tightly, and can not slide up and down the trachea.
Rapid
Sequence Induction
- When anaesthetising patients for emergency surgery, anaesthetists
use a process called a "rapid sequence induction". The
objective is to secure the airway rapidly and prevent soiling of the
lungs with gastric contents.
- We call this "the full stomach". This indicates that for
some reason, the stomach is considered full of material; the patient
need not have eaten recently.
- Reasons for having a "full stomach"
- Recent meal
- Delayed gastric emptying: trauma, acute abdomen, morphine.
- Incompetant lower oesophageal sphincter: obesity, hiatus hernia,
pregnancy
- The patient goes asleep with the aid of an intravenous induction
agent: thiopentone or propofol. These cause hypnosis and amnesia.
- To rapidly intubate the larynx, it is important to have a high
degree of muscle relaxation very quickly. The drug used for this
is suxamethonium. This acts by causing every muscle in the body to
contract, and subsequently relax. The result of this is the sudden
release of a lot of potassium into the bloodstream. Suxamethonium
is contraindicated if there is hyperkalaemia, as it may cause
cardiac arrest. Because it causes such widespread muscle
contraction (rather like "cramping"), patients usually
complain of muscle pains the next day.
- It is not conventional to premedicate patients undergoing rapid
sequence induction or to administer sedatives such as midazolam or
fentanyl prior to the administration of anaesthesia. The reason
for this is that if you are unable to intubate the patient, then
the anaesthetic agents will wear off and the patient will wake up
within 5 mins, thus not putting the airway at risk.
- We avoid manually ventilating patients undergoing rapid sequence
induction, as this inflates the stomach and encourages
regurgitation.
The
procedure of rapid sequence induction:
- Preparation:
Drugs : thiopentone, suxamethonium, atropine, ephedrine.
Endotracheal tubes: a variety of sizes available and cut and
checked (to make sure that the cuff is intact -ie. Not punctures)
Laryngoscopes 2 functioning laryngoscopes with a variety of
blades.
Suction on and under the pillow.
A Gum elastic bougie to railroad the ETT is there is
difficulty in placing the ett.
An intravenous cannula, with a free-flowing drip
Monitoring:
Blood pressure, ECG, pulse oximetery, end tidal CO2 (if available).
Assistant:
This person must be familiar with the RSI process and be able to
apply cricoid pressure. The cricoid carthilage is the ring felt below
the larynx. If this is displaced posteriorly, because it is circular
shaped and solid, it compresses and closes the oesophagus (which lies
behind it). This prevents passive regurgitation of gastric contents.
Induction:
The patient is preoxygenated for a full three minutes, to
wash all of the nitrogen out of the lungs and create a resevoir of
O2.
Thiopentone is administered, cricoid pressure is applied,
followed by suxamethonium.

The patient is asleep when the eyelash reflex is lost, and
relaxed when fasciculation stops.
The patient is intubated, the cuff inflated and the tube secured.
Cricoid pressure is not released until the anaesthetist is happy
that the tube is correctly placed. This is established by listening
for bilateral breath sounds, observing uniform bilateral chest
movement and an etCO2 trace (if available).
5. Anaesthesia
When the anaesthetist is happy that the airway is intact, he
administers the remainder of the anaesthetic agents - fentanyl,
nitrous oxide and the volatile agent which maintains anaesthesia
(e.g. isoflurane). A non depolarising neuromuscular blocker may be
added now to maintain muscle relaxation for the duration.
6. Emergence
At the completion of surgery, the anaesthetic agent is turned
off, 100% oxygen is administered, neuromuscular blockade is reversed
and the patient is permitted to emerge from anaesthesia. The risk of
aspiration of gastric contents is as high now as at the beginning.
The airway is carefully cleaned with suction and the ett remains in
situ until the patient is fully awake, lying on their side and is
able to remove the tube themselves.
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